PHYSOSTIGMINE

Pharmacokinetics

This drug is completely absorbed from the gastrointestinal and is highly distributed throughout the body; it can pass the blood brain barrier.

Pharmacodynamics

Inhibits the enzyme cholinesterase; therefore, it increases and prolongs the effect of endogenous acetylcholine at the different sites.It has no direct effect on cholinergic receptors.

Indications

• Glaucoma
• Atropine over dosage