It is derived from tricyclic antidepressant. Its pharmacological action resembles those of phenytoin, however, it is chiefly effective in the treatment of partial seizure. It is also used in the treatment of trigeminal neuralgia and manic-depressive illness.
It is powerful inducer of liver microsomal enzymes, thus accelerates the metabolism of phenytoin, warfarin, oral contraceptives and corticosteroids.
Carbamazepine causes sedation, mental disturbances and water retention.
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