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ALS7. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner due to mutation in a gene on chromosome 20ptel.

ALS6. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner due to mutation in a gene on chromosome 16q12.

ALS5. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal recessive manner due to mutation in a gene on chromosome 15q15.1-q21.1.

ALS4. A juvenile-onset form of amyotrophic lateral sclerosis (ALS) with no bulbar involvement, inherited in an autosomal dominant manner and caused by mutation in a gene on chromosome 9q34.

ALS3. An adult-onset form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner and caused by mutation in a gene on chromosome 18q21.

ALS2. A juvenile-onset form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal recessive manner and caused by mutation in the gene encoding alsin on chromosome 2q33.

ALS1. A form of amyotrophic lateral sclerosis (ALS) inherited in an autosomal dominant manner and caused by mutation in the superoxide dismutase-1 gene (SOD1) on chromosome 21q22.1. About 15 to 20% of familial ALS is type 1 (ALS1). Sporadic cases of ALS are sometimes due to new mutation in the SOD1 gene.

A classic motor neuron disease. Motor neuron diseases are progressive chronic diseases of the nerves that come from the spinal cord responsible for supplying electrical stimulation to the muscles. This stimulation is necessary for the movement of body parts. LOU GEHRIG’S DISEASE: Amyotrophic lateral sclerosis is quite a mouthful. The disease is therefore usually referred…

One of a group of diseases (called amyloidosis) in which protein deposits (amyloid) accumulate in one or more organ systems in the body, secondary amyloid is caused by a chronic infection or inflammatory disease such as rheumatoid arthritis, familial Mediterranean fever, osteomyelitis, or granulomatous ileitis. The protein deposits in this type of the disease are made up of a…

A disorder of plasma cells (special white blood cells that produce antibodies), this is one of a group of diseases (called amyloidosis) in which protein deposits (amyloid) accumulate in one or more organ systems in the body. Primary amyloidosis is the most common type of amyloidosis in many countries including the U.S. The protein deposits…