Category: At-At

A progressive disease characterized by degeneration of the nervous system manifest by poor coordination and balance (cerebellar ataxia), red eyes due to widening of small blood vessels in the conjunctiva (ocular telangiectasia), and recurrent sinus and lung infections. Abbreviated AT. Patients with AT have a striking predisposition to leukemia and lymphoma and are extremely sensitive to radiation. Other features include difficulty swallowing and slowed growth. AT is inherited as an…

Poor coordination and unsteadiness due to the brain’s failure to regulate the body’s posture and regulate the strength and direction of limb movements. Ataxia is usually due to disease in the cerebellum of the brain, which lies beneath the back part of the cerebrum.

Symbol for the ataxia telangiectasia mutated (ATM) gene. The protein made by the ATM gene functions to control the rate at which cells grow. The ATM protein does this by sending signals and modifying proteins in the cell, which then alters the function of the proteins. This protein also interacts with other proteins (for example BRCA1) to respond…

Poor coordination and unsteadiness due to the brain’s failure to regulate the body’s posture and regulate the strength and direction of limb movements. Ataxia is usually due to disease in the cerebellum of the brain, which lies beneath the back part of the cerebrum.

AT stands for adenine and thymine, a base pair in DNA. The other base pair in DNA is GC (guanine and cytosine).