Amikacin

Amikacin is a semisynthetic derivative of kanamycin; it is less toxic than the parent molecule. It is resistant to many enzymes that inactivate gentamicin and tobramycin, and it therefore can be employed against some microorganisms resistant to the latter drugs. Strains of multidrug- resistant Mycobacterium tuberculosis, including streptomycin-resistant strains, are usually susceptible to amikacin.