Allergic Disorders:-
Including urticaria, seasonal hay fever, atopic and contact dermatitis, mild blood transfusion reactions.
N.B. Their topical use is not recommended because of the risk of sensitization and a high tendency to cause eczematous reactions.
They are not effective in bronchial asthma and common cold.
Other uses:
Diphehydramine and promethazine are used as hypnotics. Diphenhydramine and orphenadrine are effective in the treatment of Parkinsonism .Dimehydrinate and promethazine are employed in the prevention and treatment of motion sickness, other vomiting disorders associated with labyrinthine dysfunction as well as nausea and vomiting associated with pregnancy. Diphenhydramine is frequently used in the treatment of cough as combination preparation with other agents.
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