Carbachol

Pharmacokinetics

It is completely absorbed from the gastro intestinal tract and is stable towards hydrolysis by cholinesterase enzyme; therefore it can be given both orally and parenteraly with almost similar dosage.

Pharmacodynamics

It has similar actions to those of acetylcholine with pronounced effects on the gastro intestinal tract and the urinary bladder

Indications

• Glaucoma
  • Retention of urine (postoperative)

• Paralytic ileus